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Session 109  Poster Abstracts
Resistance to Entry Inhibitors: Novel Agents, CCR5 Antagonists, and In Vitro Dynamics
Monday, 1 - 4 pm
Poster Hall
      616 A Novel Mechanism of Resistance to an HIV-1 Entry Inhibitor: Cleavage of the gp41 Cytoplasmic Tail by the Viral Protease
Abdul Waheed*1, S Ablan1, M Mankowski2, J Cummins2, R Ptak2, C Schaffner3, and E Freed1
1NCI-Frederick, MD, US; 2Southern Res Inst, Frederick, MD, US; and 3Rutgers Univ, New Brunswick, NJ, US
      617

HIV-1 PHENOSCRIPT ENV: A Sensitive Assay for the Detection of HIV X4 Minority Species and Determination of Non-B Subtype Viral Tropism
Vanessa Roulet*1,2,3, Vanessa Roulet*1,2,3, Vanessa Roulet*1,2,3, S Rochas1,2, S Rochas1,2, J L Labernardičre1,3, J L Labernardičre1,3, F Mammano3, J L Faudon2, N Raja2, S Lebel-Binay1, K Skrabal1,2, and K Skrabal1,2
1BioAlliance Pharma, Paris, France; 2Eurofins Viralliance Inc, Kalamazoo, MI, US; and 3INSERM U552, Paris, France
      618 HIV-1 Co-receptor Switch Induced by Antagonism to CCR5
Gemma Moncunill*, M Armand-Ugón, B Clotet, and J Esté
Fndn irsiCaixa, Badalona, Spain
      619 Longitudinal Evaluation of Viral Co-receptor Tropism Switches among HIV-infected Patients with Drug-resistant Viremia
Peter Hunt*1, W Huang2, E Coakley2, C Petropoulos2, M Bates2, R Hoh1, S Deeks1, and J Martin1
1Univ of California, San Francisco, US and 2Monogram Biosci, South San Francisco, CA, US
      620

Full Fusion Competence Rescue of the Enfuvirtide Resistant HIV-1 gp41 Genotype by a Naturally Occurring Polymorphism
Martin Tolstrup*1,2, Martin Tolstrup*1,2, J Selzer-Plön1, A Laursen1, L Bertelsen1, J Gerstoft3, M Duch2, F Pedersen2, and L Ostergaard1
1Aarhus Univ Hosp, Denmark; 2Univ of Aarhus, Denmark; and 3Rigshospitalet, Copenhagen, Denmark
      621

Characterization of New Mutational Pattern in HIV-1 gp41 Associated with T-20 Treatment
Stefano Aquaro*1,2, Stefano Aquaro*1,2, V Svicher1, R D'Arrigo3, M Santoro1, G Di Perri4, S Lo Caputo5, U Visco-Comandini3, P Narciso3, A Antinori3, and C Perno3
1Univ of Tor Vergata, Rome, Italy; 2Univ of Calabria, Rende, Italy; 3Natl Inst of Infectious Diseases, L Spallanzani, Rome, Italy; 4Hosp Amedeo di Savoia, Univ of Turin, Italy; and 5Hosp Santa Maria Annunziata, Florence, Italy
      622

Kinetics of Disappearance of Enfuvirtide-resistance HIV-1 Mutations after Drug Discontinuation
Charlotte Charpentier*1, M Jenabian2, C Piketty3, P Tisserand1, L Belec1, L Weiss3, and A Si-mohamed1
1Hosp Europeen Georges Pompidou, Paris France; 2INSERM U743, Ctr de Recherches Biomédicales des Cordeliers, Paris, France; and 3Hosp Europeen Georges Pompidou, Paris, France