Session 124 - CROI 2007

Session 124 Poster Abstracts
Immunology of HIV Infection in Children
Monday, 1 - 4 pm
Poster Hall

690	Prognostic Value of 3-Color Flow Cytometry in Advanced Pediatric HIV Disease Vincent Carey*¹, A Weinberg², S Pahwa³, A Kovacs⁴, S Burchett⁵, and ACTG 366 Study Group ¹Channing Lab, Harvard Med Sch, Boston, MA, US; ²Univ of Colorado Hlth Sci Ctr, Denver, US; ³Miller Sch of Med, Univ of Miami, FL, US; ⁴Keck Sch of Med, Univ of Southern California, Los Angeles, US; and ⁵Children's Hosp Boston, Harvard Med Sch, MA, US
691	T-cell Activation and Thymic Output Are Determinants of Viral Load in Kenyan Infants following Peripartum HIV Infection Paul Krogstad*¹, B Payne², E Obimbo², D Mbori-Ngacha², G John-Stewart^2,3, and G John-Stewart^2,3 ¹David Geffen Sch of Med, Univ of California, Los Angeles, US; ²Univ of Nairobi, Kenya; and ³Univ of Washington, Seattle, US
692	CD8⁺ T-cell Activation in Pediatric HIV Norma Pérez*, G Del Bianco, G Heresi, and J Murphy Univ of Texas Med Sch, Houston, US
693	Terminally Differentiated CD8⁺ T Cells in Vertically HIV-infected Children: Cytokine Production and HIV Gag/Pol Specificity Tim Niehues*¹, D Delbeck¹, M Siepermann¹, S Wirth², U Baumann³, U Wintergerst⁴, R Adam¹, M Jetzek-Zader¹, and O Feyen¹ ¹Univ Hosp Duesseldorf, Germany; ²Children's Hosp, Helios Klinikum Wuppertal, Witten-Herdecke Univ, Germany; ³Hannover Med Sch, Germany; and ⁴Ludwig Maximillians Univ of Munich, Children's Hosp, Germany
694	Defective CCR7 mRNA Levels Associated with Viral Load and Correlates Inversely with CD4 Count in Perinatally HIV-infected Subjects Seema Desai*, H Liu, A Chappero, N Strbo, K Arheart, G Scott, and S Pahwa Univ of Miami Miller Sch of Med, FL, US
695	Predictors of Virologic Response to ART and Characterization of Immune Repopulation in HIV-1-infected Children with Different Virologic Response to ART M Zanchetta¹, A Anselmi¹, D Vendrame¹, M Cabbia¹, O Rampon², C Giaquinto², and Anita De Rossi*¹ ¹AIDS Reference Ctr, Univ of Padova, Italy and ²Univ of Padova, Italy
696	Delayed Recovery of HIV-specific CD4-mediated Immunity in HIV-infected Children on their First HAART Regimen (PACTG P1021) Adriana Weinberg*¹, P Britto², C Hu², R Dickover³, J Patterson¹, D Smith³, H Gutzman⁴, J Kraimer⁵, M Rathore⁶, R McKinney⁷, and PACTG P1021 Team ¹Univ of Colorado Hlth Sci Ctr Sch of Med, Denver, US; ²Statistical & Data Analysis Ctr, Harvard Sch of Publ Hlth, Boston, MA, US; ³David Geffen Sch of Med, Univ of California, Los Angeles, US; ⁴Frontier Sci & Tech Res Fndn, Amherst, NY, US; ⁵Social & Sci Systems, Silver Spring, MD, US; ⁶Learning Resource Ctr, Univ of Florida Hlth Sci Ctr, Jacksonville, US; and ⁷Duke Univ Med Ctr, Durham, NC, US
697	Sustained Increased Thymic Output and Decreased Immune Activation in Children and Adolescents with High Post-therapy Viral Loads while Receiving PI-containing ART Carina Rodriguez*¹, L Yin², M Morrow¹, P Emmanuel¹, M Goodenow², and J Sleasman¹ ¹Univ of South Florida, Tampa, US and ²Univ of Florida, Gainesville, US
698	T-cell Phenotypes and Responses to Vaccines in Severely Immunocompromised HIV-infected Children Initiating HAART in PACTG 1006 Adriana Weinberg*¹, M Rigaud², P Muresan³, P LaRussa⁴, J Kraimer⁵, P Jean-Philippe⁶, J Read⁷, W Borkowsky⁸, and PACTG 1006 Team ¹Univ of Colorado Hlth Sci Ctr Sch of Med, Denver, US; ²New York Univ Med Ctr, NY, US; ³Statistical & Data Analysis Ctr, Harvard Sch of Publ Hlth, Boston, MA, US; ⁴Columbia Univ Coll of Physicians and Surgeons, New York, NY, US; ⁵Social & Sci Systems, Silver Spring, MD, US; ⁶NIH, Bethesda, MD, US; ⁷Natl Inst of Child Hlth and Human Devt, NIH, Bethesda, MD, US; and ⁸New York Univ Sch of Med, NY, US
699	Influenza Immunization Elicits Suboptimal Immune Responses in HIV-infected Children with Fully Suppressed HIV Viremia and Immune Recovery Alessandra Viganò*¹, G Zuccotti¹, P Erba¹, M Pacei², E Castelletti², V Giacomet¹, C Figini¹, E Pariani², A Amendola², and M Clerici² ¹L Sacco Hosp, Univ of Milan, Italy and ²Univ of Milan, Italy