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Session 14  Oral Abstracts
Prevention of Mother-to-Child Transmission
Monday, 4-6 pm
Room: Room 302-304
4:00 pm    42LB Extended Infant Post-exposure Prophylaxis with Antiretroviral Drugs Significantly Reduces Postnatal HIV Transmission: The PEPI-Malawi Study
Taha Taha*1, M Thigpen2, N Kumwenda1, D Hoover3, G Kafulafula4, Q Li1, L Mipando5, K Nkanaunena5, M Fowler6, and L Mofenson7
1Johns Hopkins Univ Bloomberg Sch of Publ Hlth, Baltimore, MD, US; 2CDC, Atlanta, GA, US; 3Rutgers Univ, Piscataway, NJ, US; 4Univ of Malawi Coll of Med, Blantyre; 5Johns Hopkins Univ Coll of Med, Blantyre, Malawi; 6Johns Hopkins Univ Sch of Med, Baltimore, MD, US; and 7Natl Inst of Child Hlth and Devt, NIH, Bethesda, MD, US
4:15 pm         43 Extended-dose Nevirapine to 6 Weeks of Age for Infants in Ethiopia, India, and Uganda: A Randomized Trial for Prevention of HIV Transmission through Breastfeeding
Jayagowri Sastry*1,2,3,4 and The Six Week Extended Dose Nevirapine (SWEN) Study Team
1BJ Med Coll, Pune, India; 2Johns Hopkins Univ, Baltimore, MD, US; 3Addis Ababa Univ Faculty of Med, Ethiopia; and 4Makerere Univ Sch of Med, Kampala, Uganda
4:30 pm         44 Timing of Infection Is Critical for Nevirapine Resistance Outcomes among Breastfed Subtype C HIV-1-infected Infants Exposed to Extended vs Single-dose Nevirapine Prophylaxis: The India SWEN Study
Anitha Moorthy*1, A Gupta2, G Sastry3, V Venkatramani4, R Bhosale4, V Kulkarni3, N Gupte3, C Ziemniak2, R Bollinger2, D Persaud2, and on behalf of the India SWEN Study Team
1Johns Hopkins Univ Bloomberg Sch of Publ Hlth, Baltimore, MD, US; 2Johns Hopkins Univ Sch of Med, Baltimore, MD, US; 3BJ Med Coll and Johns Hopkins Univ, Pune, India; and 4BJ Med Coll, Pune, India
4:45 pm  45aLB Prevention of Mother-to-Child Transmission of HIV-1 among Breastfeeding Mothers Using HAART: The Kisumu Breastfeeding Study, Kisumu, Kenya, 2003–2007
Timothy Thomas*1, R Masaba2, R Ndivo2, C Zeh1, C Borkowf3, M Thigpen3, K De Cock4, P Amornkul4, A Greenberg3, M Fowler3, and Kisumu Breastfeeding Study Team
1CDC Kenya, Kisumu; 2Kenya Med Res Inst, Kisumu; 3CDC, Atlanta, GA, US; and 4CDC Kenya, Kisumu
5:00 pm      45b The TEmAA ANRS 12109 Phase II Trial, Step 1: Tolerance and Viral Resistance after Single-dose Nevirapine and Short-course of Tenofovir Disoproxil Fumarate and Emtricitabine to Prevent Mother-to-Child Transmission of HIV-1
Elise Arrive*1, M L Chaix2, E Nerrienet3, S Blanche4, C Rouzioux2, J McIntyre5, P Coffie6, K Sim7, D Ekouevi6, and F Dabis1
1INSERM U593, Inst for Publ Hlth, Epi and Devt, Univ Victor Segalen, Bordeaux, France; 2Ctr Hosp Univ Necker, Univ Paris Descartes, Paris, France; 3Inst Pasteur, Phnom Penh, Cambodge; 4Hosp Necker for Sick Children, Paris, France; 5Univ of the Witwatersrand, Soweto, South Africa; 6Prgm PACCI, Abidjan Côte d`Ivoire; and 7Hosp Calmette, Phnom Penh, Cambodia
5:15 pm         46 Duration and Pattern of Breastfeeding and Postnatal Transmission of HIV: Pooled Analysis of Individual Data from a West and South African Cohort Study
Renaud Becquet*1,2,3, R Bland1,4, V Leroy2,3, N Rollins1,5, D Ekouevi2,3,6, A Coutsoudis5, F Dabis2,3, H Coovadia7, R Salamon2,3, and M L Newell1,8
1Africa Ctr for Hlth and Population Studies, Univ of KwaZulu Natal, Somkhele, South Africa; 2INSERM U593, Bordeaux, France; 3Inst for Publ Hlth, Epi and Devt, Univ Victor Segalen, Bordeaux, France; 4Univ of Glasgow, UK; 5Univ of KwaZulu Natal, Durban, South Africa; 6Ctr Hosp Univ of Treichville, Abidjan, Côte d`Ivoire; 7Ctr for HIV/AIDS Networking, Univ of KwaZulu Natal, Durban, South Africa; and 8Ctr for Paediatric Epi and Biostatistics, Inst of Child Hlth, Univ Coll London, UK
5:30 pm    47LB Population Pharmacokinetics of Tenofovir in HIV-1-infected Pregnant Women and Their Neonates: TEmAA ANRS 12109
deborah hirt*1, S urien1, E rey2, D Ekouevi3, S Blanche4, G gray5, P Coffie3, K Leang Sim6, F Dabis7, and J M Treluyer1
1Hosp Cochin, Univ Paris Descartes, France; 2Hosp Cochin, France; 3Prgm PACCI, Abidjan, Côte d`Ivoire; 4Univ Paris Descartes, France; 5Univ of the Witwatersrand, Soweto, South Africa; 6Hosp Calmette, Phnom Penh, Cambodia; and 7INSERM U593, Inst for Publ Hlth, Epi and Devt, Univ Victor Segalen, Bordeaux, France
5:45 pm         48 Effectiveness of NNRTI-containing ART in Women Previously Exposed to a Single Dose of Nevirapine: A Multi-country Cohort Study
Paul Weidle*1, J Stringer2, M McConnell1,3, J Kiarie4, T Anekthananon5, T Jariyasethpong6, D Potter2, W Mutsotso7, C Borkowf1, O Bolu1, and The NNRTI Response Study Team
1CDC, Atlanta, GA, US; 2Univ of Alabama at Birmingham, Ctr for Infectious Disease Res in Zambia, Lusaka; 3Thailand Ministry of Publ Hlth-US CDC Collaboration, Nonthaburi; 4Kenyatta Natl Hosp, Univ of Nairobi, Kenya; 5Siriraj Hosp., Mahidol Univ., Bangkok, Thailand; 6Rajavithi Hosp, Bangkok, Thailand; and 7CDC Kenya, Nairobi