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Session 170  Poster Abstracts
Hepatitis C Co-infection: Cellular Immune Responses and Pathogenesis
Monday, 1-4 pm
Room: Hall B
    1041

HIV/HCV Co-infection Results in Increased T Cell Activation and Impaired IL-7-mediated T Lymphocyte Homeostasis: Possible Exploitation as Predictors of Anti-HCV Therapy Response
G Marchetti1, Marco Bongiovanni*1, V Pegorer1, L Gazzola1, G Bellistri1, T Bini1, A Gori2, and A d'ARMINIO MONFORTE1
1San Paolo Hosp, Univ of Milan, Italy and 2San Gerardo Hosp, Monza, Italy
    1042

Immune Activation Is Not Associated with Annual Rate of CD4 Decline in HIV/HCV-co-infected Women
Roksana Karim*1, W Mack1, G Neuman1, L Spencer1, L Al-Harthi2, and A Kovacs1
1Univ of Southern California, Los Angeles, US and 2Rush Univ Med Ctr, Chicago, IL, US
    1043

Influence of HIV, HCV, and HIV/HCV-co-infection on Level, Phenotype, and Activation Status of Foxp3+CD4+ Regulatory T Cells
Norma Rallon*, M Lopez, V Soriano, J Garcia-Samaniego, M Romero, P Labarga, P Garcia-Gasco, J Gonzalez-Lahoz, and J Benito
Hosp Carlos III, Madrid, Spain
    1044

Enhanced Activation of Liver-infiltrating CD8+ T cells in HCV-infected Patients with HIV Co-infection
Henry Radziewicz*, C Ibegbu, H Scarborough, M Fernandez, M Osborn, H Hon, K Workowski, K Obideen, M Wehbi, and A Grakoui
Emory Univ, Atlanta, GA, US
    1045

HCV-specific CD4+ T Cell Responses Can Be Primed in Acute Concomitant HIV/HCV Co-infection and Are Preserved by Early ART
Julian Schulze zur Wiesch*1,2, D Pieper1, J Mohn1, T Eiermann3, A Lohse2,4, J Hauber1, I Stahmer1, and J van Lunzen5
1Heinrich Pette Inst for Experimental Virology and Immunology, Hamburg, Germany; 2Univ of Hamburg, Germany; 3Univ of Hamburg, Germany; 4Universitaetsklinikum Hamburg Eppendorf, Germany; and 5Univ of Hamburg Med Ctr, Germany
    1046

HCV Co-infection Is Associated with Increased CD4+ T Cell Apoptosis in HIV-infected Patients – Disappearance of this Effect upon Successful HAART
Christian Koerner*1, D Schulte1, B Kramer1, S Mauss2, G Schmutz2, P Hegener2, G Fatkenheuer3, J Nattermann1, U Spengler1, J Rockstroh1, and Kompetenznetz HIV/AIDS
1Univ of Bonn, Germany; 2Ctr for HIV and Hepatogastroenterology, Düsseldorf, Germany; and 3Univ of Cologne, Germany
    1047

Comparisons between Heroin Injection Drug Use and Methadone on Antigen-specific Cellular Immune Responses in HIV/HCV and HCV Infection
Camilla Graham*1, M Kress1, E Edwards2, T Heeren2, D Nunes3, P Skolnik3, S Tumilty3, R Horsburgh2, D Cotton2,3, M Koziel1, and members of CHARM
1Beth Israel Deaconess Med Ctr, Boston, MA, US; 2Boston Univ Sch of Publ Hlth, MA, US; and 3Boston Med Ctr, MA, US
    1048

HIV gp120 Sensitizes Human Hepatocytes to TRAIL-mediated Apoptosis via JNKII
Stacey Rizza*, B Shepard, G Bren, and A Badley
Mayo Clin, Rochester, MN, US
    1049

Detection of HIV in Liver Biopsies and Intrahepatic Lymphocytes
G Ma, A Barrett, K Sherman, T Shata, and Jason Blackard*
Univ of Cincinnati Coll of Med, OH, US