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Session 10
Oral Abstracts
HIV Transmission: Characteristics and Prevention
Monday, 10 am-12:15 pm
Room: Room 517b-d |
| 10:00 am 45 |
Complete HIV-1 Sequences in Acute and Early Infection Reveal the Genetic Identity, Biological Phenotype, and Precise Evolutionary Pathways of Transmitted/Founder Viruses and Their Progeny
Jesus Salazar-Gonzalez*1, M Salazar1, B Keele1, G Learn1, E Hunter2, M Markowitz3, B Haynes4, B Korber5,6, B Hahn1, and G Shaw1
1Univ of Alabama at Birmingham, US; 2Emory Univ, Atlanta, GA, US; 3Aaron Diamond AIDS Res Ctr, The Rockefellar Univ, New York, NY, US; 4Duke Univ Med Ctr, Durham, NC, US; 5Los Alamos Natl Lab, NM, US; and 6Santa Fe Inst, NM, US |
| 10:15 am 46 |
Complete Protection against Repeated Vaginal Simian HIV Exposures in Macaques by a Topical Gel Containing Tenofovir Alone or with Emtricitabine
Charles Dobard*1, U Parikh1, S Sharma1, M-E Cong1, J Smith1, G Garcia-Lerma1, F Novembre2, R Otten1, T Folks1, and W Heneine1
1CDC, Atlanta, GA, US and 2Yerkes Primate Res Ctr, Emory Univ, Atlanta, GA, US |
| 10:30 am 47 |
Prevention of Rectal Simian HIV Transmission in Macaques by Intermittent Pre-exposure Prophylaxis with Oral Truvada
Gerardo Garcia-Lerma*, M-E Cong, J Mitchell, A Youngpairoj, A Martin, D Hanson, R Otten, L Paxton, T Folks, and W Heneine
CDC, Atlanta, GA, US |
| 10:45 am 48LB |
Safety and Effectiveness of Vaginal Microbicides BufferGel and 0.5% PRO 2000/5 Gel for the Prevention of HIV Infection in Women: Results of the HPTN 035 Trial
Salim Abdool Karim*1, A Coletti2, B Richardson3, G Ramjee4, I Hoffman5, M Chirenje6, T Taha7, M Kapina8, L Maslankowski9, and L Soto-Torres10
1Ctr for the AIDS Prgm of Res in South Africa, Durban; 2Family Hlth Intl, Medford, MA, US; 3Univ of Washington, Seattle, US; 4South African Med Res Council, Durban; 5Univ of North Carolina at Chapel Hill, US; 6Univ of Zimbabwe, Harare; 7Johns Hopkins Univ Bloomberg Sch of Publ Hlth, Baltimore, MD, US; 8Ctr for Infectious Disease in Zambia, Lusaka; 9Univ of Pennsylvania, Philadelphia, US; and 10NIAID, NIH, Bethesda, MD, US |
| 11:00 am 49LB |
Cell-free Virus in Seminal Plasma is the Origin of Sexually Transmitted HIV among Men Who Have Sex with Men
David Butler*1, M Lakdawala1, D Richman1,2, S Little1, and D Smith1,2
1Univ of California, San Diego, US and 2VA San Diego Hlthcare System, CA, US |
| 11:15 am 50 |
Persistent HIV RNA Shedding in Semen despite Effective ART
Prameet Sheth*1, C Kovacs1,2, K Kemal3, B Jones1, C Laporte4, M Loutfy1,5, H Burger3, B Weiser3, R Pilon6, R Kaul1,7, and the Toronto Mucosal HIV Res Group
1Univ of Toronto, Canada; 2Maple Leaf Med Clinic, Toronto, Canada; 3Wadsworth Ctr, NY State Dept of Publ Hlth, Albany, US; 4Univ of Ottawa, Ottawa Hosp, and Ottawa Hlth Res Inst, Canada; 5Canadian Immunodeficiency Res Collaborative, Toronto; 6Ctr for Communicable Diseases and Infection Control, Publ Hlth Agency of Canada, Ottawa; and 7Univ Hlth Network, Toronto, Canada |
| 11:30 am 51 |
Detection of HIV-1 RNA in Seminal Plasma Samples from Treated Patients with Undetectable HIV-1 RNA in Blood Plasma
Anne-Genevieve Marcelin*1, R Tubiana1, S Lambert-Niclot1, G Lefebvre2, S Dominguez1, M Bonmarchand1, D Vauthier-Brouzes1, F Marguet1, G Peytavin1, C Poirot1, and the Pitie-Salpetriere AMP a Risque Viral Study Group
1Hosp Pitie-Salpetriere, Paris, France and 2Hopital Bichat-Claude Bernard, Paris, France |
| 11:45 am 52a |
ART Reduced the Rate of Sexual Transmission of HIV among HIV-discordant Couples in Rural Rakai, Uganda
Steven Reynolds*1,2, F Makumbi3, J Kagaayi4, G Nakigozi4, R Galiwongo4, T Quinn1,2, M Wawer5, R Gray5, and D Serwadda3
1NIAID, NIH, Bethesda, MD, US; 2Johns Hopkins Univ Sch of Med, Baltimore, MD, US; 3Makerere Univ Sch of Publ Hlth, Kampala, Uganda; 4Rakai Hlth Sci Prgm, Entebbe, Uganda; and 5Johns Hopkins Univ Bloomberg Sch of Publ Hlth, Baltimore, MD, US |
| 12:00 pm 52bLB |
Reduction of HIV Transmission Risk and High Risk Sex while Prescribed ART: Results from Discordant Couples in Rwanda and Zambia
Patrick Sullivan*1, K Kayitenkore2, E Chomba3, E Karita2, L Mwananyanda3, C Vwalika3, M Conkling3, N Luisi1, A Tichacek1, and S Allen1
1Emory Univ, Rollins Sch of Publ Hlth, Atlanta, GA, US; 2Project San Francisco, Kigali, Rwanda; and 3Zambia Emory HIV Res Project, Lusaka |
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