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Session 26  Poster Discussion
Themed Discussion: Genome-wide Studies of HIV Control and Disease Progression
Tuesday, 2:30-3:30 pm
Room: Room 710
      541

A Genome-wide Association Study in HIV-1 Controllers
Paul De Bakker*1,2, F Pereyra2,3, X Jia1, C Brumme1,3, N Burtt1, D Haas4, R Gulick5, D Kuritzkes2, S Deeks6, B Walker3, and Intl HIV Controllers Study
1Broad Inst of Massachusetts Inst of Tech and Harvard Univ, Cambridge, US; 2Brigham and Women`s Hosp, Harvard Med Sch, Boston, MA, US; 3Partners AIDS Res Ctr, Massachusetts Gen Hosp, Boston, US; 4Vanderbilt Univ Sch of Med, Nashville, TN, US; 5Weill Med Coll of Cornell Univ, New York, NY, US; and 6Univ of California, San Francisco, US
      542

The Role of Common Human Polymorphisms in HIV Control
Jacques Fellay*1, D Ge1, K Shianna1, S Colombo2, B Haynes1, A Telenti2, D Goldstein1, and Ctr for HIV/AIDS Vaccine Immunology (CHAVI)
1Duke Univ, Durham, NC, US and 2Univ of Lausanne, Switzerland
      543

Genome-wide Association Scan in HIV-1-infected Individuals Identifies a Variant in the C20orf151/Cables2 Gene Region Influencing Disease Course
Daniëlle Van Manen*1, N Kootstra1, B Boeser-Nunnink1, J Burger1, R Van ‘t Slot2, A Van ‘t Wout1, and H Schuitemaker1
1Academic Med Ctr, Univ of Amsterdam, The Netherlands and 2Univ Med Ctr, Utrecht, The Netherlands
      544 A Genome-wide Association Study of Time to AIDS after HIV-1 Infection
Joshua Herbeck*1, G Gottlieb1, R Detels2, S Wolinsky3, C Winkler4, S O'Brien4, J Margolick5, L Jacobson5, R Kaslow6, and J Mullins1
1Univ of Washington, Seattle, US; 2Univ of California, Los Angeles, US; 3Northwestern Univ, Chicago, IL, US; 4NCI-Frederick, MD, US; 5Johns Hopkins Univ, Baltimore, MD, US; and 6Univ of Alabama at Birmingham, US
    545a

Genome-wide Association Study of an AIDS Non-Progression Cohort Emphasizes the Role Played by HLA Genes (ANRS Genome-wide Association Study 02)
S LIMOU1,2,3, S Le Clerc1,2,3, C coulonges2,3, J-D Lelievre1,4, Y Levy1,4, J-F Delfraissy2, S Hercberg3, and Jean-Francois Zagury*1,2,3
1INSERM U955; 2ANRS Genomic Group; 3Conservatoire Natl des Art et Metiers; and 4Faculty of Med of Creteil, Univ Paris 12, France
    545b

Genome-wide Analysis of mRNA Expression and DNA Polymorphisms in Purified CD4 T Cells Isolated from HIV-1-infected Individuals
Margalida Rotger*1, K Dang2, P Descombes3, J Fellay2, D Goldstein2, and A Telenti1
1Univ of Lausanne, Switzerland; 2Duke Univ, Durham, NC, US; and 3Univ of Geneva, Switzerland
      546

Evolutionary Pattern of Host Genes Involved in HIV Infection and Pathogenesis
Millan Ortiz*1, N Guex2, I Xenarios2, and A Telenti1
1Inst of Microbio, Univ of Lausanne, Switzerland and 2VITAL-IT, Swiss Inst of Bioinformatics, Lausanne
      547

Effect of Phenotype Definition on Genome-wide Association Signals: Empirical Evaluation in HIV-1 Infection
Evangelos Evangelou*1, J Fellay2, D Goldstein2, A Telenti1, and EuroCHAVI Consortium
1Inst of Microbio, Univ Hosp Ctr and Univ of Lausanne, Switzerland and 2Ctr for Population Genomics and Pharmacogenetics, Duke Inst for Genome Sci & Policy, Durham, NC, US