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Session 30
Oral Abstracts
Mechanisms of Immunologic Control of HIV/SIV Infection
Tuesday, 4-6 pm
Room: Room 710 |
| 4:00 pm 111 |
Neutralizing Antibody Recognition of V1 in Early HIV-1 Infection
Katharine Bar*, B Keele, J Decker, J Salazar-Gonzales, M Salazar, H Li, S Wang, T Grayson, B Hahn, and G Shaw
Univ of Alabama at Birmingham, US |
| 4:15 pm 112 |
The First Emerging CD8 T Cell Responses Are a Major Determinant of Early Viral Set-Point
Hendrik Streeck*1, J Jolin1, B Yassine-Diab2, Y Qi3, D Kwon1, M Addo1, R Johnson3, B Walker1, M Carrington3, M Altfeld1, and Acute HIV Infection Network
1Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School Boston, Massachusetts, USA; 2Laboratoire d`Immunologie, Centre de Recherche du CHUM, Montreal, Quebec, Canada.; and 3Basic Research Program, SAIC-Frederick, Inc, NCI-Frederick, Frederick, Maryland, United States |
| 4:30 pm 113 |
Lytic Granule Loading of CD8+ T Cells Is Required for HIV-infected Cell Elimination Associated with Immune Control
Stephen Migueles*1, C Osborne1, A Compton1, R Joshi1, J Rood1, A Berkley1, N Cogliano-Shutta1, M Lloyd1, S Palmer2, and M Connors1
1NIAID, NIH, Bethesda, MD, US and 2SAIC, Frederick, MD, US and NCI, Frederick, MD, US |
| 4:45 pm 114 |
Cytotoxic Activity of Virus-specific CD8 T Cells Correlates with Perforin and Granzyme B Expression and Differentiation Stage but Not with Granzyme A or K
Alexandre Harari*, F Bellutti Enders, C Cellerai, and G Pantaleo
Ctr Hosp Univ Vaudois Lausanne, Switzerland |
| 5:00 pm 115 |
A Molecular Perspective of PD-1 Receptor Function
Andre Tanel*1, S Fonseca1, C Qiu1, F Procopio1, Q Eichbaum2, M El Far1, Z He1, B Walker2, E Haddad1, and R-P Sekaly1
1INSERM U743, Univ of Montreal, Hosp St-Luc, Canada and 2Howard Hughes Med Inst, Partners AIDS Res Ctr, Boston, MA, US |
| 5:15 pm 116 |
SIVD Nef Vaccination Systemically Mobilizes Natural Killer Cells
Keith Reeves*1, J Gillis1, F Wong1, Y Yu1, L Giavedoni2, A Haase3, and P Johnson1
1New England Primate Res Ctr, Harvard Med Sch, Southborough, MA, US; 2Southwest Fndn for Biomed Res, San Antonio, TX, US; and 3Univ of Minnesota Med Sch, Minneapolis, US |
| 5:30 pm 117 |
B Cells Play a Marginal Role in SIVmac239c Nef-mediated Protection against SIVmac239 Challenge
Maurus De La Rosa*1, V Evans1, S Finstad1, S Westmoreland2, A Carville2, P Johnson2, M Piatak3, D Montefiori4, N Letvin1, and J Schmitz1
1Beth Israel Deaconess Med Ctr, Harvard Med Sch, Boston, MA, US; 2New England Primate Res Ctr, Harvard Med Sch, Southborough, MA, US; 3SAIC, Frederick, MD, US and NCI, Frederick, MD, US; and 4Duke Univ Med Ctr, Durham, NC, US |
| 5:45 pm 118 |
Disruption of Env Tyrosine-dependent Sorting Signal Does Not Affect the Susceptibility of HIV-1 to Inhibition by CD8+ Cytotoxic T Lymphocytes
Justin De La Cruz*, A Ali, H Ng, and O Yang
AIDS Inst, Univ of California, Los Angeles, US |
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