Session 38 - CROI 2009

Session 38 Oral Abstracts
Emerging Patterns of Neuropathogenesis on Current ART
Wednesday, 10 am-12 noon
Room: Room 511

10:00 am 154	HIV-associated Neurocognitive Impairment Remains Prevalent in the Era of Combination ART: The CHARTER Study R Heaton¹, D Franklin¹, D Clifford², S Woods¹, M Rivera Mindt^3,4, O Vigil¹, M Taylor¹, T Marcotte¹, H Atkinson¹, and Igor Grant*¹ ¹Univ of California, San Diego, US; ²Washington Univ, St Louis, MO, US; ³Mt Sinai Sch of Med, New York, NY, US; and ⁴Fordham Univ, New York, NY, US
10:15 am 155	The Neuro-epidemiology of HIV in the United States in the Era of ART, from the National NeuroAIDS Tissue Consortium Ian Everall*¹, D Lazzaretto¹, S Letendre¹, R Ellis¹, B Gelman², S Morgello³, E Singer⁴, I Grant¹, E Masliah¹, and F Vaida¹ ¹HIV Neurobehavioral Res Ctr, Univ of California, San Diego, US; ²Univ of Texas Med Branch, Galveston, US; ³Mt Sinai Med Ctr, New York, NY, US; and ⁴Univ of California, Los Angeles, US
10:30 am 156	Persistence of HIV-related Brain Injury in the HAART Era: A Multicenter Proton Magnetic Resonance Spectroscopy Study Bradford Navia*¹, J Harezlak², S Buchthal³, R Cohen⁴, M Taylor⁵, G Schifitto⁶, E Singer⁷, T Campbell⁵, E Daar⁸, C Yiannoutsos², and HIV Neuroimaging Consortium ¹Tufts Univ Sch of Med, Boston, MA, US; ²Indiana Univ Sch of Med, Indianapolis, US; ³Univ of Hawaii, Manoa, US; ⁴Warren Alpert Med Sch, Brown Univ, Providence, RI, US; ⁵Univ of California, San Diego Med Ctr, US; ⁶Univ of Rochester Sch of Med, NY, US; ⁷Univ of California, Los Angeles, US; and ⁸Harbor-Univ of California, Los Angeles Med Ctr, US
10:45 am 157	Additive Effects of Aging and HIV Serostatus on Cerebral Blood Flow Beau Ances*¹, J Yeh², F Vaida², C Liang², R Buxton², S Letendre², I Grant², and R Ellis² ¹Washington Univ Sch of Med, St Louis, MO, US and ²HIV Neurobehavioral Res Ctr, Univ of California, San Diego Sch of Med, US
11:00 am 158	Replication and Clonal Amplification of Compartmentalized HIV-1 Populations in the Cerebrospinal Fluid of Subjects with HIV-associated Dementia Gretja Schnell*¹, R Price², S Spudich², and R Swanstrom¹ ¹Univ of North Carolina at Chapel Hill, US and ²San Francisco Gen Hosp, Univ of California, San Francisco, US
11:15 am 159	Limited Expression of a Subset of Viral Genomes Present in Brain that Is Distinct from HIV DNA or RNA in Lymphoid Tissues William Pasutti*¹, S Pillai², P Li¹, C Ahlgren¹, S Yukl², K Fujimoto¹, R Ellis³, E Masliah³, and J Wong^1,2 ¹Northern California Inst for Res and Ed, San Francisco, US; ²Univ of California, San Francisco, US; and ³Univ of California, San Diego, US
11:30 am 160	Mitochondrial Sub-haplogroups and Peripheral Neuropathy during ART among Non-Hispanic Black Participants in AIDS Clinical Trials Group Study 384 J Canter¹, G Robbins², D Selph¹, D Clifford³, A Kallianpur¹, R Shafer⁴, S Levy¹, D Murdock¹, D Haas¹, Todd Hulgan*¹, and the ACTG Study 384 and New Work Concept Sheet 273 Teams ¹Vanderbilt Univ, Nashville, TN, US; ²Harvard Univ, Boston, MA, US; ³Washington Univ, St Louis, MO, US; and ⁴Stanford Univ, CA, US
11:45 am 161	Predicting Neuropathy Risk before Stavudine Prescription: An Algorithm for Minimizing Neurotoxicity in Resource-limited Settings Catherine Cherry*¹, J Affandi², E Yunihastuti³, S Vanar⁴, D Imran³, A Kamarulzaman⁴, K Smyth⁵, A Wadley⁶, P Kamerman⁶, and P Price⁷ ¹Macfarlane Burnet Inst, Alfred Hosp, Monash Univ, Melbourne, Australia; ²Murdoch Univ, Perth, Australia; ³Pokdisus Clinic, Cipto Mangunkusumo Hosp, Univ of Indonesia, Jakarta; ⁴Univ of Malaya, Kuala Lumpur, Malaysia; ⁵Australian Natl Univ, Canberra; ⁶Univ of the Witwatersrand, Johannesburg, South Africa; and ⁷Royal Perth Hosp, Univ of Western Australia