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Session 121  Poster Abstracts
Pharmacokinetics and Pharmacogenetics of ARVs
Wednesday, 1-2:30 pm
Poster Hall
      690

Analyses of Efavirenz Metabolism in vivo in Genetically Characterized Individuals
Julia Di Iulio*, M Rotger, A Fayet, L Decosterd, A Telenti, and the Swiss HIV Cohort Study
Univ Hosp Ctr and Univ of Lausanne, Switzerland
      691

Inter- and Intra-patient Variability in Nevirapine Plasma Concentrations in HIV-infected Cambodian Patients and the Effect of CYP2B6 Genetic Polymorphism: ANRS 12154 Study
M Chou1, J Bertrand2, O Segeral3, C Verstuyft3, L Borand4, E Comets2, L Becquemont3, V Ouk5, F Mentré2, Anne-Marie Taburet*3, and the ANRS 12154 Study Group
1Faculty of Pharmacy Phnom Penh Cambodia; 2INSERM U738 Bichat University Paris France; 3Hospital Bicêtre APHP, Paris France; 4Pasteur Institute Phnom Penh Cambodia; and 5Hospital Calmette Phnom Penh Cambodia
      692 Concentrations of Efavirenz in Hair Are Strongly Correlated with Virologic Response
Monica Gandhi*1, N Ameli1, P Bacchetti1, Y Huang1, S Gange2, K Anastos3, A Levine4, M Cohen5, M Young6, R Greenblatt1, and Women's Interagency HIV Study (WIHS)
1Univ of California, San Francisco, US; 2Johns Hopkins Univ Bloomberg Sch of Publ Hlth, Baltimore, MD, US; 3Albert Einstein Univ, Bronx, NY, US; 4Univ of Southern California and City of Hope Natl Med Ctr, Los Angeles, US; 5Cook County Hosp, Chicago, IL, US; and 6Georgetown Univ, Washington, DC, US
      693

Raltegravir Has No Influence on UGT1A4/2B7 when Using Lamotrigine as a Phenotypic Probe
Matthijs Van Luin*1,2, A Colbers1, E Van Ewijk-Beneken Kolmer1, C Verwey-Van Wissen1, M Van Der Kolk1, A Hoitsma1, H Da Silva3, P Koopmans1, and D Burger1
1Radboud Univ Nijmegen Med Ctr, Nijmegen, The Netherlands; 2Rijnstate Hosp, Arnhem, The Netherlands; and 3Merck Res Labs Europe, Paço D`Arcos, Portugal
      694

A Pharmacological Strategy for Switching from Efavirenz to Nevirapine
Steve Taylor*1, A Berry1, N Dufty1, S Barrett1, and A Owen2
1Birmingham Heartlands Hosp, UK and 2Univ of Liverpool, UK
      695 Therapeutic Drug Monitoring of ART: A Cochrane Systematic Review
Tamara Kredo*1, J-S Van Der Walt1, N Siegfried2, and K Cohen1
1Univ of Cape Town, South Africa and 2South African Cochrane Ctr, Med Res Council, Cape Town