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Session 125
Poster Abstracts
Alterations in Blood Lipids and Body Fat
Monday, 1-2:30 pm
Poster Hall |
712
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Ezetimibe Is Safe and Effective in Combination with Statin Therapy for the Treatment of Elevated Low-density Lipoprotein Cholesterol in HIV-infected Subjects: Results of ACTG Protocol A5209
Dominic Chow*1, H Chen2, M Glesby3, A Busti4, S Souza1, S Kohrs5, J Wu2, J Andersen2, S Koletar6, and ACTG Protocol A5209
1Univ of Hawaii, Honolulu, US; 2Statistical and Data Analysis Ctr, Harvard Sch of Publ Hlth, Boston, MA, US; 3Weill Med Coll of Cornell Univ, New York, NY, US; 4Texas Tech Univ Hlth Sci Ctr, Dallas, US; 5Univ of Cincinnati, OH, US; and 6Ohio State Univ, Columbus, US |
713
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Atherogenic Lipid Profile in Treated HIV Patients with Increased Visceral Adiposity: Association with More Severe Cardiovascular Disease Risk Parameters and Response to Tesamorelin, a Growth Hormone-releasing Factor Analogue
Julian Falutz*1, J-C Mamputu2, C Marsolais2, D Potvin2, M Zoltowska2, G Soulban2, D Kotler3, and S Grinspoon4
1McGill Univ Hlth Ctr, Montreal Gen Hosp, Canada; 2Theratechnologies Inc, Montreal, Canada; 3St Luke`s Roosevelt Hosp Ctr, Columbia Univ, Coll of Physicians and Surgeons, New York, NY, US; and 4Massachusetts Gen Hosp, Harvard Med Sch, Boston, US |
| 714 |
A Pilot Study to Determine the Effect on Dyslipidemia of the Addition of Tenofovir to Stable Background ART in HIV-infected Subjects: Results from the A5206 Study Team
Marisa Tungsiripat*1, D Kitch2, M Glesby3, S Gupta4, J Mellors5, L Moran6, L Jones7, B Alston-Smith8, J Rooney9, and J Aberg10
1Cleveland Clinic, OH, US; 2Harvard Sch of Publ Hlth, Boston, MA, US; 3Cornell Univ, New York, NY, US; 4Indiana Univ Sch of Med, Indianapolis, US; 5Univ of Pittsburgh Med Ctr, PA, US; 6ACTG Operations Ctr, Silver Spring, MD, US; 7Frontier Sci & Tech Res Fndn, Amherst, NY, US; 8NIAID, NIH, Bethesda, MD, US; 9Gilead Sci, Foster City, CA, US; and 10New York Univ Sch of Med, NY, US |
715
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Contribution of Multiple Genetic Variants Identified through Genome-wide Analysis to Metabolic Complications Associated with ART
Margalida Rotger*1, C Bayard1, P Taffe2, R Martinez1, A Telenti1, P Tarr3, and the Swiss HIV Cohort Study
1Univ Hosp Ctr and Univ of Lausanne, Switzerland; 2Swiss HIV Cohort Study Data Ctr, Lausanne; and 3Cantonal Hosp, Bruderholz, Switzerland and Univ of Basel, Switzerland |
| 716 |
The Genetic Determinants of High-density Lipoprotein Cholesterol Changes in HIV-1-infected Adults on Efavirenz-based Regimens
Tabitha Mahungu*1,2, D Nair1, C Smith1, F Turner1, M Youle1, M Johnson1, D Egan2, S Khoo2, D Back2, and A Owen2
1Royal Free NHS Trust, London, UK and 2Univ of Liverpool, UK |
717
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Human Subcutaneous Adipose Tissue Is Highly Sensitive to Lipopolysaccharide- and Nelfinavir-induced Inflammation while Visceral Fat Is Resistant
C Vatier1, S Leroyer1, J Quette1, N Brunel2, C Chapron3, Jacqueline Capeau*1, and B Antoine1
1CDR Saint-Antoine InsermU893, Paris, France; 2IFR65, Paris, France; and 3Cochin Hospital, APHP Paris, France |
718
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Efavirenz Causes Accumulation of Intracellular Lipids in Hepatic Cells
A Blas-García1, D Ballesteros2, D Monleón1, J Morales1, M Rocha1,3, V Víctor1,3, N Apostolova2, and Juan Esplugues*2
1Univ of Valencia, Spain; 2University of Valencia and CIBERehd, Valencia, Spain; and 3Fundacion Hospital Universitario Dr.Peset, Valencia, Spain |
| 719 |
Gene Expression Is Differentially Altered in Visceral vs Subcutaneous Adipose Tissue from HIV-1-infected, HAART-treated, Patients with Lipodystrophy
Pere Domingo*1, J Villarroya2, J Gallego-Escuredo2, J Domingo2, M Alegre1, M Gutierrez1, M Mateo1, E Targarona1, F Villarroya2, and M Giralt2
1Hospital de la Santa Creu i Sant Pau. Barcelona and 2University of Barcelona, and Institut de Biomedicina de la Universitat de Barcelona (IBUB) |
| 720 |
Nef Alters Cortical Actin Ring Dynamics and Inhibits Glucose Uptake by Adipocytes; a Contribution to Insulin Resistance in HIV-infected People
Laura Cheney*1, M O'Hara1, J Hou1, S Morrison1, J Pessin2, and R Steigbigel1
1Stony Brook Univ, NY, US and 2Albert Einstein Coll of Med, Bronx, NY, US |
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