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Session 24-Oral Abstracts
Antiretroviral-based Prevention: Exposure and Efficacy
Thursday, 9:30-11 am; Room 2011 |
| 9:30 am 83 |
Efficacy of Intermittent Prophylaxis with Tenofovir and Emtricitabine against Rectal SHIV Transmission in Macaques and Relationship to Systemic and Mucosal Drug Levels
Gerardo Garcia-Lerma*1, M-E Cong1, Q Zheng1, A Holder1, A Martin1, C-C Lin1, R Otten1, W Lee2, C-P Pau1, and W Heneine1
1CDC, Atlanta, GA, US and 2Gilead Sci, Foster City, CA, US |
| 9:45 am 84LB |
Protection of Rhesus Macaques from Vaginal Infection by Maraviroc, an Inhibitor of HIV-1 Entry via the CCR5 Co-receptor
R Veazey1, T Ketas2, J Dufour1, P Klasse2, and John Moore*2
1Tulane Natl Primate Res Ctr, Covington, LA, US and 2Weill Cornell Med Coll, New York, NY, US |
| 10:00 am 85 |
Antiretrovirals for Prevention: Maraviroc Exposure in the Semen and Rectal Tissue of Healthy Male Volunteers after Single and Multiple Dosing
Kevin Brown*, K Patterson, S Malone, N Shaheen, H Prince, J Dumond, M Spacek, P Heidt, M Cohen, and A Kashuba
Univ of North Carolina at Chapel Hill, US |
| 10:15 am 86 |
Validating Measures of Tenofovir Drug Exposure in a US Pre-exposure Prophylaxis Trial
Albert Liu*1,2, E Vittinghoff2, M Gandhi2, Y Huang2, K Chillag3, R Wiegand3, P Anderson4, R Grant2, R Greenblatt2, and S Buchbinder1,2
1San Francisco Dept of Publ Hlth, CA, US; 2Univ of California, San Francisco, US; 3CDC, Atlanta, GA, US; and 4Univ of Colorado Denver, US |
| 10:30 am 87LB |
PRO2000 Vaginal Gel is Ineffective in Preventing HIV Infection: Results of the MDP301 Phase III Microbicide Trial
M Chisembele1, A Crook2, M Gafos3, R Hayes4,5, U Jentsch6, A Kamali7, C Lacey8, Sheena McCormack*9, G Ramjee10, H Rees11, and the MDP Team
1Univ Teaching Hosp, Lusaka, Zambia; 2Med Res Council Clin Trials Unit, London, UK; 3Africa Ctr for Hlth and Population Studies, Mtubatuba, South Africa; 4London Sch of Hygiene and Tropical Med, UK; 5NIMR/AMREF/LSHTM Collaborative Res Projects, Mwanza, Tanzania; 6Contract Lab Svcs, Johannesburg, South Africa; 7Med Res Council/Uganda Virus Res Inst, Entebbe; 8Univ of York, UK; 9Imperial Coll London, UK; 10Med Res Council, Durban, South Africa; and 11Univ of the Witwatersrand, Johannesburg, South Africa |
| 10:45 am 88LB |
Association of Expanded HAART Coverage with a Decrease in New HIV Diagnoses, Particularly among Injection Drug Users in British Columbia, Canada
Julio Montaner*, E Wood, T Kerr, B Yip, V Lima, K Shannon, R Harrigan, and R Hogg
BC Ctr for Excellence in HIV/AIDS, Vancouver, Canada |
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