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Session 32-Themed Discussion
TD: HIV Drug Resistance in Breastfeeding Infants Exposed to ART
Thursday, 1-2 pm; Room 2005
      917

Transmission of NVP-resistant HIV-1 to Infants by Breastfeeding Observed after Maternal sdNVP
Sandra Dross1, I Beck1, M Micek2,3, A J Blanco3,4, L Matunha4, P Montoya3,4, E Matediana5, S Gloyd2,3, S Gantt1,3, and L Frenkel1,3
1Seattle Children’s Res Inst, WA, US; 2Hlth Alliance Intl, Seattle, WA, US; 3Univ of Washington, Seattle, US; 4Hlth Alliance Intl, Beira, Mozambique; and 5Mozambique Ministry of Hlth, Beira
      918

Comparison of NVP Resistance among HIV-infected Infants Who Received Extended NVP Plus ZDV Prophylaxis vs Extended NVP Prophylaxis Alone: The PEPI-Malawi Study
Jessica Lidstrom1, D Hoover2, N Kumwenda3, Q Li3, L Mofenson4, M G Fowler1,5, A Taylor5, M Thigpen5, T Taha3, and S Eshleman1
1Johns Hopkins Univ Sch of Med, Baltimore, MD, US; 2Rutgers Univ, Piscataway, NJ, US; 3Johns Hopkins Univ Bloomberg Sch of Publ Hlth, Baltimore, MD, US; 4NIH, Rockville, MD, US; and 5CDC, Atlanta, GA, US
      919 Delayed Clearance of High-frequency NVP-resistant Viremia in the First Year of Life in HIV-infected Infants Who Received Extended NVP for Prevention of Breast-milk Transmission: Implications for Early Therapy
Deborah Persaud, C Ziemniak, and the Ethiopian SWEN Study Team
Johns Hopkins Univ Sch of Med, Baltimore, MD, US
      920

Multi-class Drug Resistance Arises Frequently in HIV-infected Breastfeeding Infants Whose Mothers Initiate HAART Postpartum
Jessica Lidstrom1, L Guay1, P Musoke2, M Owor3, C Onyango-Makumbi3, J Church1, S Omer4, B Jackson1, and S Eshleman1
1Johns Hopkins Univ Sch of Med, Baltimore, MD, US; 2Makerere Univ, Kampala, Uganda; 3Makerere Univ-Johns Hopkins Univ Res Collaboration, Kampala, Uganda; and 4Emory Univ, Atlanta, GA, US