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Session 63-Poster Abstracts
Evolution of HIV Co-receptor Usage
Wednesday, 2-4 pm; Poster Hall
      270

CD4+ T Cell Turnover Is Related to Chemokine Receptor Expression and HIV Viral Co-receptor Tropism
Derek Macallan*1, Y Zhang1, C de Lara2, A Worth2, and P Beverley2
1St George’s, Univ of London, UK and 2Univ of Oxford, UK
      271

Sensitivity to CCR5 and Fusion Inhibitors Decreases over the Course of HIV-1 Infection
Nikolaos Chatziandreou*1, I Freitas1, G Fenton1, A Kamat1, G Kirk2,3, S Mehta2,3, and M Sagar1
1Brigham and Women’s Hosp, Harvard Med Sch, Boston, MA, US; 2Johns Hopkins Univ Sch of Med, Baltimore, MD, US; and 3Johns Hopkins Univ Bloomberg Sch of Publ Hlth, Baltimore, MD, US
      272

Adaptation to Use Low Levels of the CD4 Receptor is an Early Event in the Process of Co-receptor Switching in R5 SHIV-infected Rapid Progressors
Ke Zhuang*1, A Finzi2, S Tasca1, M Shakirzyanova1, S Westmoreland3, J Sodroski2, and C Cheng-Mayer1
1Aaron Diamond AIDS Res Ctr, The Rockefeller Univ, New York, NY, US; 2Dana-Farber Cancer Inst, Harvard Med Sch, Boston, MA, US; and 3New England Primate Res Ctr, Harvard Med Sch, Southborough, MA, US
      273 Evolution of Env Protein and Co-receptor Usage during Pregnancy in Women Infected with B vs Non-B HIV-1 Subtypes
Doris Ransy*, J Couto, J Samson, N Lapointe, M Boucher, and H Soudeyns
Ctr Hosp Univ Sainte-Justine, Montreal, Canada
      274

X4 Emergence in a Seropositive R5 SHIVSF162P3N-infected Macaque and in a Macaque Infected with Its Molecular Clone
Wuze Ren*1, S Tasca1, A Gettie1, J Blanchard2, and C Cheng-Mayer1
1Aaron Diamond AIDS Res Ctr, The Rockefeller Univ, New York, NY, US and 2Tulane Natl Primate Res Ctr, Tulane Univ Med Ctr, Covington, LA, US
      275

Ultra-deep Pyrosequencing Captured Low Frequency CXCR4 Virus Populations Co-archived with CCR5 Virus in Peripheral Blood Lymphocytes from HIV-infected Therapy-naïve Children
Li Yin*1, L Liu1, Y Sun1, R Gray1, A Lowe1, W Hou1, J Sleasman2, and M Goodenow1
1Univ of Florida, Gainesville, US and 2Univ of South Florida, St Petersburg, US
      276

Detection of Predicted CXCR4-using HIV-1 Variants in Longitudinally Obtained Paired Plasma and Peripheral Blood Mononuclear Cells Samples Using 454-sequencing
Angélique van ’t Wout*1, L Swenson2, W Dong2, H Schuitemaker1, and R Harrigan2
1Academic Med Ctr, Amsterdam, The Netherlands and 2BC Ctr for Excellence in HIV/AIDS, Vancouver, Canada
      277

Prediction of X4-tropic HIV from Proviral Envelope Sequence in Patients with Suppressed Viral Load on ART
Elizabeth White*1, M Balamane1, K Henry2, D Katzenstein1, and ACTG 5102
1Stanford Univ, CA, US and 2Univ of Minnesota, Minneapolis, US
      278

Prevalence of CXCR4-using Subtype C HIV-1 Infection among Treatment-naive Women: Results from the Mashi Study
Nina Lin*1,2, L Smeaton3, F Giguel2, R Musonda4, J Makhema4, S Lockman1,3,4,5, M Essex3,4, and D Kuritzkes1,5
1Harvard Med Sch, Boston, MA, US; 2Massachusetts Gen Hosp, Boston, US; 3Harvard Sch of Publ Hlth, Boston, MA, US; 4Botswana-Harvard AIDS Inst, Gaborone; and 5Brigham and Women’s Hosp, Boston, MA, US