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Session 109-Poster Abstracts
Detection of Minority Resistance Mutations
Friday, 2-4 pm; Poster Hall |
563
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Sensitive Quantification of Drug-resistant Minor Variants Using a Simplified Design that Tolerates Viral Sequence Heterogeneity
Teri Liegler*1, M Abdel-Mohsen1, R Atchison2, S Zhang3, E Fiss3, and R Grant1,2
1Univ of California, San Francisco, US; 2Gladstone Inst of Virology and Immunology, San Francisco, CA, US; and 3Roche Molecular Systems, Pleasonton, CA, US |
564
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Detection of Minority K65R Variants in NRTI-naive Subtype B and C HIV-1-infected Individuals
J-F Li1, J Lipscomb1, X Wei1, M Owen1, N Martinson2, L Morris3, W Heneine1, and Jeffrey Johnson*1
1CDC, Atlanta, GA, US; 2Univ of the Witwatersrand, Johannesburg, South Africa; and 3Natl Inst for Communicable Diseases, Johannesburg, South Africa |
| 565 |
Sentinel Mutations in Standard Population Sequencing Can Predict the Presence of RT Major Mutations Detected Only by 454-Pyrosequencing
V Svicher1, C Alteri1, I Abbate2, A Bruselles2, B Bartolini2, F Forbici2, G Rozera2, M M Santoro1, M R Capobianchi2, and Francesca Ceccherini-Silberstein*1
1Univ of Rome Tor Vergata, Italy and 2INMI L Spallanzani, Rome, Italy |
| 566 |
Primary Mutations Associated with Resistance to Raltegravir Are Not Detectable by Pyrosequencing in Integrase Inhibitors-naive Patients
Francesca Ceccherini-Silberstein*1, D Armenia1, R D’Arrigo2, I Vandebroucke3, H Van Marck3, G Rizzardini4, P Narciso2, A Antinori2, L Stuyver3, and C F Perno1
1Univ of Rome Tor Vergata, Italy; 2INMI L Spallanzani, Rome, Italy; 3Virco BVBA, Mechelen, Belgium; and 4Hosp Luigi Sacco, Milan, Italy |
567
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Ultradeep Sequencing Refines Phenotypic Predictions to Darunavir, Etravirine, and Other Protease and Reverse Transcriptase Inhibitors in Heavily Pre-treated Subjects Infected with Multidrug Resistant HIV-1
Francisco Codoñer*1, C Pou1, A Thielen2, F García3, R Delgado4, D Dalmau5, M Álvarez-Tejado6, B Clotet1,7, L Ruiz1, R Paredes1,7, and the PRIUS Study Group
1Fndn irsiCaixa, Autonomous Univ of Barcelona, Spain; 2Max Planck Inst for Informatics, Saarbrücken, Germany; 3Hosp San Cecilio, Granada, Spain; 4Hosp 12 de Octubre, Madrid, Spain; 5Mútua de Terrassa, Spain; 6Roche Diagnostics SL, Sant Cugat del Vallès, Spain; and 7Fndn Lluita contra la SIDA, Hosp Germans Trias i Pujol, Badalona, Spain |
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