Home Search Abstracts Browse Oral Sessions Browse Poster Sessions

 

Session 122-Poster Abstracts
Pharmacokinetics and Drug Interactions of Protease Inhibitors
Friday, 2-4 pm; Poster Hall
      617

Identification of Novel Factors that Influence Atazanavir Exposure in a Diverse Population of HIV-infected Women under Conditions of Actual Use
Monica Gandhi*1, S Gange2, C Ponath1, K Anastos3, P Bacchetti1, G Sharp4, M Cohen5, M Young6, H Minkoff7, R Greenblatt1, and Women’s Interagency HIV Study
1Univ of California, San Francisco, US; 2Johns Hopkins Univ Bloomberg Sch of Publ Hlth, Baltimore, MD, US; 3Albert Einstein Univ, Bronx, NY, US; 4NIAID, NIH, Bethesda, MD, US; 5Rush Med Coll, Chicago, IL, US; 6Georgetown Univ, Washington, DC, US; and 7Lincoln Med and Mental Hlth Ctr, Bronx, NY, US
      618 A Population Pharmacokinetic Model Illustrates an Association between a Pregnane-X Receptor Polymorphism and Boosted Atazanavir Clearance
Alessandro Schipani*1, M Siccardi1,2, M Boffito3, A D’Avolio2, S Bonora2, G Davies1, S Khoo1, D Back1, G Di Perri2, and A Owen1
1Univ of Liverpool, UK; 2Univ of Turin, Amedeo di Savoia Hosp, Italy; and 3St Stephens Ctr, Chelsea and Westminster Fndn Trust, London, UK
      619

Immune Activation Mediated Change in the Plasma Binding Protein Alpha-1-Acid Glycoprotein Alters Plasma Lopinavir Concentrations
Igho Ofotokun*1, J Lennox1, M Eaton1, J Ritchie1, and E Acosta2
1Emory Univ, Atlanta, GA, US and 2Univ of Alabama at Birmingham, US
      620

Pharmacokinetic Interactions between Buprenorphine/Naloxone and Once-daily Lopinavir/riitonavir
Douglas Bruce*1, F Altice1, D Moody2, G Morse3, L Andrews1, S-N Lin2, W Fang2, Q Ma3, and G Friedland1
1Yale Univ AIDS Prgm, New Haven, CT, US; 2Univ of Utah, Salt Lake City, US; and 3Univ of Buffalo, NY, US
      621

Bidirectional Pharmacokinetic Interaction between Posaconazole and Fosamprenavir
R Brüggemann1, M van Luin1, M van den Dungen1, A Colbers1, B Schouwenberg1, R le Blanc2, C Pharo3, and David Burger*1
1Radboud Univ Nijmegen Med Ctr, The Netherlands; 2GlaxoSmithKline BV, Zeist, The Netherlands; and 3GlaxoSmithKline Pharma Europe, Brentford, UK
      622 Laboratory Macrophage Screening Assays Predict Pharmacokinetics of Controlled Release Nanoformulated Antiretroviral Drugs
Ari Nowacek*, Z Ma, J McMillan, J Huang, S P Bathena, C Fletcher, A Anderson, Y Alnouti, H Dou, and H Gendelman
Univ of Nebraska Med Ctr, Omaha, US