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Session 176-Poster Abstracts
Impact of ART on Disease Pathogenesis in Children
Thursday, 2-4 pm; Poster Hall |
886
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CD4 T Cell Depletion, and Not Age, May Be a Driver of Abnormal CD4 Cell Compartments in HIV-infected Children Initiating ART in Uganda Victor Musiime*1, A S Walker2, P Musoke3, P Nahirya Ntege4, G Pimundu1, M Spyer2, D Sefe5, P Pala4, D Gibb2, N Klein5, and the ARROW Trial Team
1Joint Clin Res Ctr, Kampala, Uganda; 2Med Res Council Clin Trials Unit, London, UK; 3Pediatric Infectious Diseases Ctr, Mulago, Uganda; 4Med Res Council/Uganda Virus Res Inst, Entebbe; and 5Inst of Child Hlth, London, UK |
887
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ART within 12 Weeks of Age Is Associated with Induction of IL-7 Production, Boosted Naïve T Cell Frequency and Lower Immune Activation Livio Azzoni*1, E Papasavvas1, A Foulkes2, X Yin1, D Glencross3, W Stevens3, V Maino4, M Cotton5, A Violari3, and L Montaner1
1The Wistar Inst, Philadelphia, PA, US; 2Univ of Massachusetts, Amherst, US; 3Univ of the Witwatersrand, Johannesburg, South Africa; 4BD Biosci, San Jose, CA, US; and 5Stellenbosch Univ, Cape Town, South Africa |
888
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HIV-1 Viremia or Delayed ART Initiation Associate with Increased LPS Plasma Levels in Perinatally Infected Infants Emmanouil Papasavvas*1, L Azzoni1, A Violari2, M Cotton3, A Foulkes4, X Yin1, D Glencross2, W Stevens2, J McIntyre2, and L Montaner1
1The Wistar Inst, Philadelphia, PA, US; 2Univ of the Witwatersrand, Johannesburg, South Africa; 3Tygerberg Children’s Hosp, Stellenbosch Univ, Cape Town, South Africa; and 4Univ of Massachusetts, Amherst, US |
889
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Associations of Pro-inflammatory Cytokine Levels with Lipid Profiles, Growth, and Body Composition in HIV-infected Children Initiating or Changing ART J Cervia1, C Chantry2, M Hughes3, Carmelita Alvero*3, W Meyer4, J Hodge5, P Borum6, J Moye7, S Spector8, and P1010 Study Team
1Albert Einstein Coll of Med, Bronx, NY, US; 2Univ of California, Davis Med Ctr, Sacramento, US; 3Ctr for Biostatistics in AIDS Res, Harvard Sch of Publ Hlth, Boston, MA, US; 4Quest Diagnostics, Baltimore, MD, US; 5Frontier Sci and Tech Res Fndn, Amherst, NY, US; 6Univ of Florida, Gainesville, US; 7Natl Inst of Child Hlth and Human Devt, NIH, Bethesda, MD, US; and 8Univ of California, San Diego, US |
| 890 |
Immunologic and Viral Dynamics among HIV-infected Children after Planned Treatment Interruption: A Substudy of the Pediatric European Network for Treatment of AIDS 11 Trial. D Sefe1, Nigel Klein*1, I Mosconi2, E Ricci2, H Castro3, M Jacobsen1, S Bernardi4, D Pillay5, D Gibb3, A De Rossi2, and on behalf of the PENTA Steering Committee
1Inst of Child Hlth, Univ Coll London, UK; 2AIDS Reference Ctr, Univ of Padova, Italy; 3Med Res Council Clin Trials Unit, London, UK; 4Ospedale del Bambino Gesù, Rome; and 5Univ Coll London and Hlth Protection Agency, UK |
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