|
Session 7-Oral Abstracts
HIV–Host Interaction
Monday, 10 am-12 noon; Room 302-304 |
| 10:00 am 21 |
Comparative Analysis of Genomic Features of Human HIV-1 Infection and Primate Models of SIV Infection
Margalida Rotger*1, J Dalmau2, A Rauch3, P McLaren4, S Bosinger5, J Fellay1, H Günthard6, G Silvestri5, J Martinez-Picado2,7, and A Telenti1,8
1Univ Hosp and Univ of Lausanne, Switzerland; 2Fndn irsiCaixa, Badalona, Spain; 3Univ Hosp Bern, Switzerland; 4Harvard Med Sch, Boston, MA, US; 5Emory Univ, Atlanta, GA, US; 6Univ Hosp Zurich, Switzerland; 7Inst Catalana de Recerca i Estudis Avancats, Barcelona, Spain; and 8Swiss HIV Cohort Study, Lausanne |
| 10:15 am 22LB |
Genetic Variation in the HIV Genome as Study Phenotype in Human Genome-wide Association Analysis
Jacques Fellay*1, J Snoeck1, S Alizon2, V von Wyl3, T Stalder4, A Rauch5, H Günthard3, S Bonhoeffer4, A Telenti1, and Swiss HIV Cohort Study
1Univ of Lausanne, Switzerland; 2UMR2724, Inst for Res and Devt, Natl Ctr for Sci Res, Montpellier, France; 3Univ Hosp Zurich, Switzerland; 4Swiss Federal Inst of Tech, Zurich; and 5Univ Hosp Bern, Switzerland |
| 10:30 am 23 |
SIV Infection Induces Increased Trafficking of pDC to Gut Mucosa
Keith Reeves*, T Evans, J Gillis, P Rajakumar, Y Kuzmichev, and P Johnson
Harvard Med Sch, Southborough, MA, US |
| 10:45 am 24 |
Spontaneous Shedding of Soluble gp120 from Primary HIV Envelopes Is Highly Variable between AIDS Patients and Correlates with Enhanced Infection of Cells Expressing Low CD4
Megan Mefford*1,2, E Thomas1, K Kunstman3, S Wolinsky3, and D Gabuzda1,2
1Dana-Farber Cancer Inst, Boston, MA, US; 2Harvard Med Sch, Boston, MA, US; and 3Northwestern Univ, Chicago, IL, US |
| 11:00 am 25 |
Analysis of HIV DNA Molecules in Paired Peripheral Blood and Lymph Node Tissue Samples from Chronically Infected Patients
Lina Josefsson*1,2,3, S Palmer1,2,3, J Casazza4, D Ambrozak4, M Kearney3, W Shao5, J Mellors6, J Albert1,2, J Coffin7, and F Maldarelli3
1Swedish Inst for Infectious Disease Control, Solna; 2Karolinska Inst, Solna, Sweden; 3HIV Drug Resistance Prgm, NCI-Frederick, MD, US; 4NIAID, NIH, Bethesda, MD, US; 5Info Systems Prgm/Advanced Biomed Computing Ctr, SAIC-Frederick, Inc, NCI-Frederick, MD, US; 6Univ of Pittsburgh, PA, US; and 7Tufts Univ, Boston, MA, US |
| 11:15 am 26 |
Down-regulation of CCR5 by Its Ligands Decreases Number of Target Cells for HIV-1 in GBV-C-infected Individuals
Molly Perkins*1,2, J Liebner1, D Himelfarb1, H Edward1, J Brenchley3, J Stapleton4, S Rowland-Jones2,5, X Xu2, A McMichael2, and D Douek1
1Vaccine Res Ctr, NIAID, NIH, Bethesda, MD, US; 2Weatherall Inst of Molecular Med, Univ of Oxford, UK; 3NIAID, NIH, Bethesda, MD, US; 4Univ of Iowa, Iowa City, US; and 5MRC Gambia, Fajara |
| 11:30 am 27 |
Co-infection with GBV-C Reduces CD4 and CD8 Activation and Proliferation in Subjects with Detectable HIV Viral Load
Jack Stapleton*1, K Chaloner1, J Zhang1, D Klinzman1, J Martinson2, J Xiang1, S Desai2, and A Landay2
1Iowa City VAMC and Univ of Iowa, US and 2Rush Univ, Chicago, IL, US |
| 11:45 am 28LB |
An Intrinsic Inhibitor of CDK9-mediated Transcriptional Elongation of HIV-1 in CD4 T Cells from Elite Controllers
J Huang1, C Li1, T Cung1, H Chen1, J Beamon1, K Seiss1, M Carrington1, B Walker1, X Yu1, and Mathias Lichterfeld*2
1Ragon Inst of MGH, MIT, and Harvard, Charlestown, MA, US and 2Massachusetts Gen Hosp, Boston, US |
|
