Session 20 - CROI 2008

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Session 20 Oral Abstracts
Insights into Neuropathogenesis
Tuesday, 10-11:30 am
Room: Room 302-304

10:00 am 67	Reducing the Prevalence of Primary HIV Brain Pathology by Antiretrovirals Ian Everall*¹, F Vada¹, S Letendre¹, D Lazzaretto¹, B Gelman², S Morgello³, E Singer⁴, R Ellis¹, E Masliah¹, I Grant¹, and National NeuroAIDS Tissue Consortium and the UCSD HIV Neurobehavioral research Center ¹Univ of California, San Diego, US; ²Univ of Texas Med Branch, Galveston, US; ³Mt Sinai Med Ctr, New York, NY, US; and ⁴Univ of California, Los Angeles, US
10:15 am 68	Low-grade Immune Restoration Disease May Limit Recovery from HIV-associated Neurocognitive Impairment Scott Letendre*, R Ellis, L Cysique, M Cherner, S Gibson, R Heaton, A McCutchan, and The HNRC Group Univ of California, San Diego, US
10:30 am 69	Elevated Plasma Endotoxin Associated with Monocyte Activation and Reduced BDNF in AIDS Patients with Dementia Petronela Ancuta*¹, K Kunstman², E Y Kim², P Autissier³, M Mefford⁴, D Stone⁵, S Wolinsky², and D Gabuzda⁴ ¹Univ of Montreal, Canada; ²Northwestern Univ, Chicago, IL, US; ³Beth Israel Deaconess Med Ctr, Boston, MA, US; ⁴Dana-Farber Cancer Inst, Boston, MA, US; and ⁵Lemuel Shattuck Hosp, Jamaica Plain, MA, US
10:45 am 70	HIV Infection of the Cerebrospinal Fluid of Elite Controllers John Probasco*¹, S Deeks¹, E Lee¹, R Hoh¹, T Liegler¹, R Price¹, and S Spudich¹ ¹Univ of California, San Francisco, US
11:00 am 71	Influence of Immunological, Virological, and Radiological Determinants in the Clinical Outcome of Patients with Progressive Multifocal Leukoencephalopathy A Marzocchetti¹, T Tompkins¹, D Clifford², R Gandhi³, S Kesai⁴, J Berger⁵, D Simpson⁶, A DeLuca⁷, and Igor Koralnik*⁸ ¹Beth Israel Deaconess Med Ctr, Harvard Med Sch, Boston, MA, US; ²Washington Univ Sch of Med, Seattle, US; ³Massachusetts Gen Hosp, Harvard Med Sch, Boston, US; ⁴Brigham and Women`s Hosp, Boston, MA, US; ⁵Univ of Kentucky Coll of Med; ⁶Mt Sinai Med Ctr, New York, NY, US; ⁷Catholic Univ, Rome, Italy; and ⁸Beth Israel Deaconess Med Ctr, Harvard Med Sch, Boston, MA, US
11:15 am 72	Natural Genetic Resistance to Lentiviral CNS Disease: A Neuroprotective MHC Class I Allele in SIV-infected Macaques Joseph Mankowski*¹, S Queen¹, C Fernandez², P Tarwater³, J Karper¹, R Adams¹, and S Kent² ¹Johns Hopkins Univ, Baltimore, MD, US; ²Univ of Melbourne, Australia; and ³Univ of Texas Hlth Sci Ctr at Houston, Sch of Publ Hlth, El Paso, US