Session 51 - CROI 2008

Home

Session 51 Poster Abstracts
Viral Envelope: Tropism Co-receptor Studies
Tuesday, 1-4 pm
Room: Hall D

241	Selection of Replication-competent Strains of Simian Immunodeficiency Virus Which Are Deficient in Sites for Carbohydrate Attachment Elizabeth Stansell* and R Desrosiers New England Primate Res Ctr, Harvard Med Sch, Southborough, MA, US
242	A Single Residue in the HIV-1 Envelope V3 Domain Modulates Exposure of the CD4 Binding Site Rebecca Lynch*¹, R Rong¹, W Honnen², J Mulenga³, S Allen¹, J Blackwell¹, A Pinter², S Gnanakaran⁴, and C Derdeyn¹ ¹Emory Univ, Atlanta, GA, US; ²Univ of Med and Dentistry of New Jersey, New Jersey Med Sch, Newark, US; ³Zambia Blood Transfusion Svc, Lusaka; and ⁴Los Alamos Natl Lab, NM, US
243	Functional Analysis of Intracellular Targeting Motifs within HIV-1 Envelope Cytoplasmic Domain Sushma Bhakta*, E Hunter, P Spearman, and N Tsurutani Emory Univ, Atlanta, GA, US
244	Cross-reactive HIV-neutralizing Human Monoclonal Antibody Recognizes Novel Conformational Epitope on gp41 and Lacks Reactivity against Self-antigens Mei-Yun Zhang*^1,2, B Vu¹, M Alam³, R Ruprecht⁴, G Quinnan⁵, S Jiang⁶, D Montefiori⁷, C Broder⁵, B Haynes³, and D Dimitrov¹ ¹NCI-Frederick, MD, US; ²SAIC-Frederick and NCI-Frederick, MD, US; ³Human Vaccine Inst, Durham, NC, US; ⁴Dana-Farber Cancer Inst, Boston, MA, US; ⁵Uniformed Svcs Univ of the Hlth Sci, Bethesda, MD, US; ⁶Lindsley F Kimball Res Inst, New York Blood Ctr, NY, US; and ⁷Duke Univ Med Ctr, Durham, NC, US
245	Genotypic and Phenotypic Analysis of HIV-1 env Gene Populations In Subjects with Dual or Mixed Entry Phenotypes Milloni Patel*^1,2, G Schnell^1,2, M Pagan^1,2, and R Swantrom^1,2 ¹Univ of North Carolina at Chapel Hill, US and ²Ctr For AIDS Res, Univ of North Carolina at Chapel Hill, US
246	Characterization of V2 and V3 Envelope Determinants and their Correlation with Co-receptor Usage from a Cohort of East London Patients Infected with HIV-1 Clade CRF02_AG Ronald D'Amico*^1,2, H Dreja², K Aubin³, C Orkin⁴, J Hand⁴, C DeSouza⁴, M Dittmar², and A McKnight² ¹London Sch of Hygiene and Tropical Med, UK; ²Barts and the London, Queen Mary`s Univ, UK; ³Wohl Virion Ctr, Univ Coll London, UK; and ⁴St Bartholomew`s Hosp, London, UK
247	X4-tropic and Dualtropic Subtype C Biological Clones from Syncytia Inducing Isolates Elizabeth Johnston White*, B McColgan, S Kassaye, and D Katzenstein Stanford Univ, Palo Alto, CA, US
248	Variation in HIV-1 R5 Macrophage-tropism Correlates with Sensitivity to Reagents that Block Envelope:CD4 Interactions P Peters¹, M Duenas-DeCamp¹, M Sullivan¹, R Brown², C Ankghuambom², K Luzuriaga¹, J Robinson³, D Burton⁴, J Ball², and Paul Clapham*¹ ¹Univ of Massachusetts Med Sch, Worcester, US; ²Univ of Nottingham, UK; ³Tulane Univ Med Ctr, New Orleans, LA, US; and ⁴Scripps Res Inst, La Jolla, CA, US
249	HIV-1 Viruses with Different Co-receptor Tropisms Are Not Highly Compartmentalized in the Peripheral Blood William Ince*, P Harrington, K Dang, G Schnell, J Eron, C Burch, and R Swanstrom Univ of North Carolina at Chapel Hill, US
250	Low CCR5 Expression Levels on Primary CD4⁺ Lymphocytes Are a Major Obstacle to CCR5-mediated Infection by R5X4 Viruses Lamorris Loftin*, L Wang, Y Yi, J Isaacman-Beck, M Kienzle, and R Collman Univ of Pennsylvania, Philadelphia, US
251	The gp41 Transmembrane Subunit of HIV-1 Envelope Influences CD4 Receptor-dependent Virus Entry Jonathan Toma*, S Fransen, T Wrin, J Whitcomb, N Parkin, C Petropoulos, and W Huang Monogram Biosci, South San Francisco, CA, US
252	Susceptibility of Human Prostate to HIV-1 Infection A Le Tortorec¹, A P Satie¹, H Denis¹, L Havard², N Rioux-Leclercq³, A Ruffault², B Jegou¹, and Nathalie Dejucq-Rainsford*¹ ¹INSERM U625, Rennes, France; ²Ctr Hosp Univ Regional Pontchaillou, Rennes, France; and ³Ctr Hosp Univ Regional Pontchaillou, Rennes, France